Aging skin collagen degradation

Hydrolyzed Collagen Type 2 Aka collagen peptides

  • Maintain healthy cartilage
  • Support skin connectivity
  • Structure joints
  • Reduce wrinkle depth and fine lines
  • Reduce skin dryness (face and body)

Collagen constitutes 30% of the human protein matrix. After age twenty-five production declines.

Collagen composes approximately 30% of the human protein matrix. Of the twenty eight collagen variations, type 2 is responsible for structuring joints, cartilage, and tissue. Vital to skin, hair, nails and tendons, collagen production begins to decrease around age twenty five.

Hydrolyzed collagen is partially broken down collagen (peptides), a dietary form that increases the bioavailability of the protein. In clinical trials oral supplementation of hydrolyzed type II collagen has shown to significantly improve pain relief for individuals suffering from joint pain, rheumatoid arthritis, and osteoarthritis [2, 3, 4, 5, 8, 9, 12].

Cosmetically collagen is crucial to skin, nails, and hair health. Considering wrinkles form when collagen fibrils in dermal layers degrade it is vital to strengthen and support active collagen protein and dermal collagen supply. Evidence has shown that maintaining stable and healthy collagen levels throughout life naturally supports smooth skin. Collagen supplements in general and hydrolyzed collagen supplements in particular provide a simple and bioavailable means of maintaining a healthy supply of the most important protein in you. Numerous collagen supplementation studies have demonstrated improvements in skin dryness, hydration, moisture retention and elasticity leading to a noticeable reduction in facial dryness, fine lines and wrinkle depth [1, 6, 7, 10]. Show moreHide Text...

Sources

  • Asserin, J., Lati, E., Shioya, T., & Prawitt, J. (2015). The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: Evidence from an ex vivo model and randomized, placebo‐controlled clinical trials. Journal of Cosmetic Dermatology, 14(4), 291-301.
  • Bakilan, F., Armagan, O., Ozgen, M., Tascioglu, F., Bolluk, O., & Alatas, O. (2016). Effects of Native Type II Collagen Treatment on Knee Osteoarthritis: A Randomized Controlled Trial/ Diz Osteoartritli Hastalarda Nativ Tip 2 Kollajen Tedavisinin Degerlendirilmesi: Randomize Kontrollü Çalisma. Eurasian Journal of Medicine, 48(2), 95-101.
  • Barnett, M., Combitchi, D., & Trentham, D. (1996). A pilot trial of oral type II collagen in the treatment of juvenile rheumatoid arthritis. Arthritis & Rheumatism, 39(4), 623-628.
  • Barnett, M., Kremer, J., St. Clair, E., Clegg, D., Furst, D., Weisman, M., . . . Trentham, D. (1998). Treatment of rheumatoid arthritis with oral type II collagen: Results of a multicenter, double‐blind, placebo‐controlled trial. Arthritis & Rheumatism, 41(2), 290-297.
  • Benito-Ruiz, P., Camacho-Zambrano, M., Carrillo-Arcentales, J., Mestanza-Peralta, M., Vallejo-Flores, C., Vargas-Lpez, S., . . . Zurita-Gavilanes, L. (2009). A randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfort. International Journal of Food Sciences and Nutrition, 2009, Vol.60(S2), P.99-113, 60(S2), 99-113.
  • Borumand, Maryam, & Sibilla, Sara. (2015). Effects of a nutritional supplement containing collagen peptides on skin elasticity, hydration and wrinkles. Journal of Medical Nutrition and Nutraceuticals, 4(1), 47.
  • Campos Mbg, P. (2015). An Oral Supplementation Based on Hydrolyzed Collagen and Vitamins Improves Skin Elasticity and Dermis Echogenicity: A Clinical Placebo-Controlled Study. Clinical Pharmacology & Biopharmaceutics, 04(03), Clinical Pharmacology & Biopharmaceutics, 2015, Vol.04(03).
  • Crowley, D. C., Lau, F. C., Sharma, P., Evans, M., Guthrie, N., Bagchi, M., Bagchi, D., Dey, D. K., … Raychaudhuri, S. P. (2009). Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. International journal of medical sciences, 6(6), 312-21.
  • Effects of oral administration of Type II collagen on rheuma. (1993). Science, 261(5129), 1727.
  • Proksch, E., Segger, D., Degwert, J., Schunck, M., Zague, V., & Oesser, S. (2013). Oral Supplementation of Specific Collagen Peptides Has Beneficial Effects on Human Skin Physiology: A Double-Blind, Placebo-Controlled Study. Skin Pharmacology and Physiology, 27(1), 47-55.
  • Ricard-Blum S. (2011). The collagen family. Cold Spring Harbor perspectives in biology, 3(1), a004978. doi:10.1101/cshperspect.a004978
  • T, W., L, L., N, C., P, C., K, T., & A, G. (2017). Efficacy of Oral Collagen in Joint Pain - Osteoarthritis and Rheumatoid Arthritis. Journal of Arthritis, 06(02), Journal of Arthritis, 2017, Vol.06(02).